RENTON, Wash. (AP) Seahawks defensive end Jadeveon Clowney and linebacker Mychal Kendricks have been ruled out for Sunday’s game against the Carolina Panthers.

Meanwhile, cornerback Shaquill Griffin and defensive end Ziggy Ansah are questionable.

Clowney missed a pair of days this week in practice after coming down with the flu, which had previously hit several teammates in recent weeks. Clowney is also dealing with a core muscle injury that will need to be managed the rest of the season. He had initially been listed as questionable for Sunday before the team downgraded him to out before heading for the airport.